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To make himself resistant against poisonous serpent , the paranoid Pontic King Mithridates is rumored to have rent small everyday doses of venom .
Scientists think they might have discovered an easier way .
New Gallery: Snakes of the World
Immune cells responsible for the fluid noses and itchy eyes associate withasthmaandallergyattacks could help protect us against thevenomof certain snakes and insects , a raw subject show .
The finding overturn a established wisdom in music that theimmune systemexacerbates the effects of deadly bite and stings . The revised thought could lead to new antivenom treatments , the researchers say .
Mast cells release a extensive orbit of biological compounds that promote redness and other change to weave when triggered by parasites , bacteria or foreign heart and soul such as venom . In some people , they can be touch off by irritants such as pollen , causingallergicreactions .
Scientists previously thought that mast cellular phone energizing in response to chemicals in spitefulness made the bite and confidence game of snakes and insects worse . But the new study , detail in the July 28 issue of the journalScience , finds that a protein , telephone carboxypeptidase A and let go of by mast cells , actually helps break down maliciousness .
When exposed to mole viper venom , mice who had normal floor of mast cell could withstand 10 metre the dosage of spitefulness than computer mouse with no mast mobile phone . The gnawer demonstrate similar effect when tested with the venom of westerly diamondback rattlesnakes , southern Denisonia superba snakes and even a mintage of honeybee .
" The mast cellular telephone significantly limit not only the toxicity , but also the death rate associated with the malice , " said study team member Stephen Gail of the Stanford University School of Medicine .
Snake bite carry vary measure of spite , and mast cell appear to be most helpful when the amount of venom drive home is below or near the lethal dose . The research worker are presently testing to see whether mast cellphone in humans respond in the same way as mouse mast cells do .
